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Vitamins & vitamin-like compounds

Vitamin K

Vitamin K1 (phylloquinone) and vitamin K2 forms, including MK-7

Vitamin K is a fat-soluble vitamin family, not an acute nootropic. Current active listings include K1 1% powders and K2 MK-7 powders or capsules; compare the labelled vitamin K amount, rather than bulk powder grams, before comparing price.

Fat SolubleLimited Human EvidenceForm Dependent EvidenceMedication Interaction RiskAnticoagulant Caution
Updated August 2026/4 min read/5 citations
Reviewed by the NootropicsIndex editorial team.Method: prioritize cited human research and official safety or regulatory sources; compare retailer-listed prices without endorsing products.Affiliate disclosure
01

What is it?

Vitamin K is a form-dependent nutrient family

1

Vitamin K includes phylloquinone (K1) and menaquinones (K2), including MK-7. Product labels can differ by form, concentration, and serving amount, so K1 bulk powders and K2 capsules or powders are not automatically like-for-like.

Essential nutrient does not mean nootropic4
Vitamin K is essential for normal physiology, but the cognition literature describes observed relationships as interesting rather than definitive. That does not establish an acute focus, memory, or mental-energy benefit from supplementation.
02

Names, aliases and forms

Common NameVitamin K
Active ConstituentsPhylloquinone; Menaquinone-7
AbbreviationsK1; K2 MK-7
Chemical Name2-methyl-3-phytyl-1,4-naphthoquinone
Molecular FormulasC31H46O2; C46H64O2
InchikeysMBWXNTAXLNYFJB-NKFFZRIASA-N; RAKQPZMEYJZGPI-LJWNYQGCSA-N
Pubchem Cids5284607; 5287554
03

Mechanisms of action

Vitamin-K-dependent protein activation

1

Vitamin K is a coenzyme for a carboxylase involved in making vitamin-K-dependent proteins, including proteins in normal blood-clotting biology. This essential function does not demonstrate a same-day nootropic effect.

04

Potential effects and evidence map

Vitamin K is essential for vitamin-K-dependent protein activation, including normal blood-clotting biology. K1 and K2 forms should not be assumed to be interchangeable shopper units. A review of the cognition literature describes associations as interesting but not definitive, so current evidence does not establish vitamin K supplementation as a focus, memory, or mental-energy enhancement strategy.

Effect domainMagnitudeGrade
Focus / attention4
UnknownConfidence: Medium

Current clinical literature does not establish vitamin K supplements as an acute focus or attention enhancer.

Note Reported cognition associations do not establish a causal nootropic benefit.

0/5
E
05

Typical dosages and timing

Adults age 19+190-120 mcg/day

The U.S. Adequate Intake is 90 mcg/day for adult women and 120 mcg/day for adult men. This is a nutrient-reference context, not a universal dose recommendation for every K1 or K2 product or a reason to change an anticoagulant-managed routine.

06

Safety, side effects and risk profile

Interaction risk1
Confidence: High

Warfarin and similar vitamin-K-antagonist anticoagulants require a consistent vitamin K intake from food and supplements; do not make sudden changes without clinician guidance.

Note This is a targeted medication interaction, not a general warning for all users.

5/5
A
07

Interactions and cautions

Medication interaction1

Warfarin, phenprocoumon, acenocoumarol, and tioclomarol antagonize vitamin K activity. Sudden changes in vitamin K intake can alter anticoagulant effects, so any supplement change requires clinician-guided medication context.

09

Practical buying and quality notes

  • The current catalog has 25 active Vitamin K listings, mostly powders. A K1 1% bulk powder price per gram is not comparable with a K2 MK-7 capsule or powder until the label identifies the active form, concentration, and microgram serving.
  • Before considering two offers as alternatives, identify whether each label names K1 or K2/MK-7, whether a powder is diluted or concentrated, and how many micrograms of vitamin K are in a serving. Inventory counts and price rails can change; the product label controls the comparison.
10

FAQ

Is vitamin K1 the same as vitamin K2 MK-7?

1

No. K1 is phylloquinone, while K2 includes menaquinones such as MK-7. Supplements can contain different vitamin K forms, so form and labelled amount should be checked before comparing products or transferring evidence.

Does vitamin K improve focus?

4

Current clinical literature does not establish vitamin K supplementation as an acute focus or attention enhancer. Essential nutrient roles and reported cognition associations do not prove a cognitive-enhancement effect.

11

References

  1. NIH Office of Dietary Supplements. Vitamin K Fact Sheet for Health Professionals.
  2. PubChem Compound Summary for CID 5284607, Phylloquinone.
  3. PubChem Compound Summary for CID 5287554, Menaquinone-7.
  4. Alisi L, Cao R, De Angelis C, et al. The Relationships Between Vitamin K and Cognition: A Review of Current Evidence. Front Neurol. 2019.
  5. U.S. Food and Drug Administration. Information for Consumers on Using Dietary Supplements.
Note

This page is informational and summarizes available evidence. It is not medical advice, a recommendation, or a substitute for guidance from a qualified clinician.