L-Tetrahydropalmatine: A Comprehensive Overview of its Nootropic Properties
L-Tetrahydropalmatine (L-THP) is a natural alkaloid found in several plants, including Corydalis yanhusuo, Stephania cepharantha, and Sinomenium acutum. It is also known as tetrahydropalmatine, THP, and corydaline. L-THP has been used in traditional Chinese medicine for centuries and is now gaining attention as a potential nootropic supplement.
Description
L-THP is a chiral molecule, meaning it has two forms that are mirror images of each other. The two forms are known as the (R)- and (S)-enantiomers. The (R)-enantiomer is the form found in nature and is the form used in traditional Chinese medicine. The (S)-enantiomer is the form used in modern nootropic supplements.
L-THP is a dopamine receptor agonist, meaning it binds to dopamine receptors in the brain and activates them. It is also an acetylcholinesterase inhibitor, meaning it blocks the enzyme that breaks down acetylcholine, a neurotransmitter involved in learning and memory.
Positive Effects
- May improve cognitive function
- May reduce anxiety and stress
- May improve mood
- May improve sleep quality
- May reduce inflammation
Possible Negative Effects
- May cause headaches
- May cause nausea
- May cause dizziness
- May cause dry mouth
- May cause insomnia
Dosage
The recommended dosage of L-THP is between 50-200 mg per day. It is best to start with a lower dose and gradually increase it to the desired level. It is important to note that L-THP is not regulated by the FDA and should be used with caution.
History
L-THP has been used in traditional Chinese medicine for centuries. It was first isolated from the plant Corydalis yanhusuo in the late 19th century. Since then, it has been studied for its potential medicinal properties, including its nootropic effects. In recent years, it has become increasingly popular as a nootropic supplement.
L-THP is gaining attention as a potential nootropic supplement due to its ability to improve cognitive function, reduce anxiety and stress, improve mood, improve sleep quality, and reduce inflammation. It is important to note that L-THP is not regulated by the FDA and should be used with caution.